Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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301
Tocris Bioscience™ MRT 68921 dihydrochloride
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ULK inhibitor
| Chemical Name or Material | N-[3-[[5-Cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide dihydrochloride |
|---|---|
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C25H34N6O.2HCl |
| Formula Weight | Observed MW: 507.5 |
| Assay Percent Range | >98% |
302
Tocris Bioscience™ Ropinirole
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CAS: 91374-20-8 Molecular Formula: C16H25ClN2O
| CAS | 91374-20-8 |
|---|---|
| Molecular Formula | C16H25ClN2O |
303
Tocris Bioscience™ LY 2087101
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CAS: 913186-74-0 Molecular Formula: C15H11FN2OS2
| CAS | 913186-74-0 |
|---|---|
| Molecular Formula | C15H11FN2OS2 |
304
Tocris Bioscience™ AR-C 69931 Tetrasodium Salt
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Low molecular weight, organic compound that may help regulate biological process.
305
Tocris Bioscience™ PAG 3'-piperazine
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Functionalized cereblon ligand for PROTAC development
306
Tocris Bioscience™ TCS ERK 11e
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CAS: 896720-20-0 Molecular Formula: C24H20Cl2FN5O2
| CAS | 896720-20-0 |
|---|---|
| Molecular Formula | C24H20Cl2FN5O2 |
307
R&D Systems™ Cy5-Fuc Labeled N3f (Cy5-N3f)
Used as a ligand for lectins and to study glycan protein interaction
308
Tocris Bioscience™ L-AP4
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CAS: 23052-81-5 Molecular Formula: C4H10NO5P
| CAS | 23052-81-5 |
|---|---|
| Molecular Formula | C4H10NO5P |
309
Tocris Bioscience™ Disulfide biotin azide
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Azide-activated biotinylation reagent; labels alkyne moieties via copper-catalyzed click chemistry
310
Tocris Bioscience™ Ac-Cys-NHMe
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Building block for the lysine acylation using conjugating enzymes (LACE) technique
| Target | Unnatural Amino Acids |
|---|---|
| CAS | 10061-65-1 |
| Chemical Name or Material | (2R)-2-(Acetylamino)-3-mercapto-N-methylpropanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C6H12N2O2S |
311
Tocris Bioscience™ GW 5074
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 220904-83-6 Molecular Formula: C15H8Br2INO2
| CAS | 220904-83-6 |
|---|---|
| Molecular Formula | C15H8Br2INO2 |
312
Tocris Bioscience™ Gisadenafil besylate
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CAS: 334827-98-4 Molecular Formula: C29H39N7O8S2
| CAS | 334827-98-4 |
|---|---|
| Molecular Formula | C29H39N7O8S2 |
313
Tocris Bioscience™ TCS PIM-1 1
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CAS: 491871-58-0 Molecular Formula: C18H11BrN2O2
| CAS | 491871-58-0 |
|---|---|
| Molecular Formula | C18H11BrN2O2 |
314
Tocris Bioscience™ CU-76
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective inhibitor of cyclic GMP-AMP synthase (cGAS)
315
Tocris Bioscience™ AZ1 USP25/28 inhibitor
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Selective USP25 and USP28 inhibitor
| Target | USP28 |
|---|---|
| CAS | 2165322-94-9 |
| Purity | 0.98 |
| Chemical Name or Material | 2-[[[5-Bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]ethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H16BrF4NO2 |