Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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| Target | TERT |
|---|---|
| CAS | 666699-46-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-(3-Chloro-4-fluorophenyl)-4-fluoro-3,5-dimethylbenzenesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H12ClF2NO2S |
Tocris Bioscience™ AP 1867
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Selective binding ligand for FKBP12F36V
| Target | TAG Degradation Platforms |
|---|---|
| CAS | 195514-23-9 |
| Purity | 98% |
| Chemical Name or Material | (1R)-1-[3-(Carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl (2S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C38H47NO11 |
Thermo Scientific Chemicals Milnacipran hydrochloride
CAS: 101152-94-7 Molecular Formula: C15H23ClN2O
| CAS | 101152-94-7 |
|---|---|
| Molecular Formula | C15H23ClN2O |
Tocris Bioscience™ Ribociclib
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Dual cdk4/cdk6 inhibitor; orally bioavailable
(+)-Aphidicolin, MP Biomedicals™
CAS: 38966-21-1 Molecular Formula: C20H34O4 Synonym: aphidicolin, 38966-21-1, ICI 69653, (+)-Aphidicolin, (3 R,4 R,4 aR,6 AS,8 R,9 R,11 AS,11 bS)-4,9-bis(hydroxymethyl)-4,11 b-dimethyltetradecahydro-8,11 A-methanocyclohepta[a]naphthalene-3,9-diol
| CAS | 38966-21-1 |
|---|---|
| Synonym | aphidicolin, 38966-21-1, ICI 69653, (+)-Aphidicolin, (3 R,4 R,4 aR,6 AS,8 R,9 R,11 AS,11 bS)-4,9-bis(hydroxymethyl)-4,11 b-dimethyltetradecahydro-8,11 A-methanocyclohepta[a]naphthalene-3,9-diol |
| Molecular Formula | C20H34O4 |
Tocris Bioscience™ DMHBO+
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Fluorescent upon binding to Chili aptamer; for imaging RNA in cells
| CAS | 533-50-6 |
|---|---|
| Molecular Formula | C4H8O4 |
Tocris Bioscience™ RA 2
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Potent negative modulator of KCa2.3 and KCa3.1 channels
| Target | Ca2+-Activated Potassium Channel Modulators |
|---|---|
| CAS | 1867107-62-7 |
| Purity | 0.98 |
| Chemical Name or Material | 1,3-Phenylenebis(methylene)bis(3-fluoro-4-hydroxybenzoate) |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H16F2O6 |
Tocris Bioscience™ GSK'872
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Potent and selective RIP3 kinase inhibitor
| CAS | 1346546-69-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H17N3O2S2 |
| Formula Weight | 383.49 |
Tocris Bioscience™ E 2012
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γ-secretase modulator; Notch-sparing
| CAS | 870843-42-8 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (3E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-2-piperidone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H26FN3O2 |
| Formula Weight | 419.49 |
Tocris Bioscience™ FC 11
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Highly potent focal adhesion kinase (FAK) Degrader (PROTAC™)
Tocris Bioscience™ CEP
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Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells
| CAS | 56425-91-3 |
|---|---|
| Molecular Formula | C15H15F3N2O2 |